Microbiome-targeted Diet Therapy in Ulcerative Colitis
ConditionUlcerative Colitis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Minnesota
About this trial
The central objective of this proposal is to test a novel diet capable of meeting the elevated protein requirements in ulcerative colitis (UC), while simultaneously decreasing microbial hydrogen sulfide (H2S) production in the colon with fiber.
Eligibility criteria
Qualifiers
Ability and willingness to provide informed consent
Age at least 18 years old
Diagnosis of UC based on clinical and endoscopic criteria
UC duration of at least 3 months
Disqualifiers
Moderate or severe UC as defined by UCEIS ≥5
History of stomach surgery or bowel resection
Antibiotic use within 3 months
Anticipated antibiotic exposure during the study period (e.g. perioperative antibiotics)
Trial design
Treatments tested in this trial
- High Protein, High Fiber (HPHF) Diet
Treatment groups
40 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov