Microplastic Exposure From Clear Aligner Wear (MPE)
ConditionMicroplastic Exposure
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age10-75
SponsorUniversity of North Carolina, Chapel Hill
About this trial
An observational longitudinal study measuring microplastic exposure and physiologic uptake in orthodontic patients receiving clear aligner treatment.
Eligibility criteria
Qualifiers
Individuals (all sexes, genders, races, and ethnicities) aged at least 10 years (in adult dentition) and at most 75 years
Receiving comprehensive, Phase II orthodontic treatment with clear aligner therapy
Stable physical health (ASA I or II), as determined by study coordinator or PI
Able to comprehend and follow requirements of study (including availability on scheduled visit dates)
Disqualifiers
Receiving orthodontic treatment with fixed appliances
Receiving hybrid treatment with fixed appliances and aligners
Receiving Phase I orthodontic treatment with fixed appliances
Established history of severe xerostomia (dry mouth), severe periodontal disease with actively bleeding gums, significant oral abrasions/ulcers or growths, current alcohol abuse, and/or recreational drug abuse
Trial design
Treatments tested in this trial
- Clear Aligner Treatment
Treatment groups
150 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov