Dietary protein intake is essential for tissue renewal and growth. Current recommendations for protein intake are based on studies using egg protein as reference protein. Egg protein is an animal-based protein with a high quality. Protein quality is determined by the composition of (essential) amino acids and digestibility. Therefore, different proteins have a different quality. Due to the environmental crisis, an increasing number of people consumes more plant-based proteins. These plant-based proteins often have a lower protein quality compared to animal-based proteins. Therefore, the aim of this study is to investigate whether optimal protein intake depend on protein quality. The optimal protein intake of an animal-based protein with a high quality (milk) will be compared to the optimal protein intake of a plant-based protein with a low quality (wheat).
Aged between 65-85 years
BMI between 18.5-30 kg*m^-2
Healthy, recreationally active (maximal one intensive exercise training per week)
No physical limitations (i.e., able to perform all activities associated with daily living independently)
Smoking
Diagnosed musculoskeletal disorders
Use of any medications known to affect protein metabolism (i.e., corticosteriods, non-steroidal anti-inflammatories)
Chronic use of gastic acid-suppressing medication or anti-coagulants
Parallel
MILK
Other interventionDrink containing amino acids in the composition of milk protein
WHEAT
Other interventionDrink containing amino acids in the composition of wheat protein
Differences in protein intake to maximize whole-body protein synthesis rates in older adults based on consumption of milk protein or wheat protein
Estimated Average Requirement (EAR) to maximize whole-body protein synthesis rates in healthy older adults based on milk protein
The Recommended Daily Allowance (RDA) to maximize whole-body protein synthesis rates in older adults based on milk protein
The Estimated Average Requirement (EAR) to maximize whole-body protein synthesis rates in older adults based on wheat protein
The Recommended Daily Allowance (RDA) to maximize whole-body protein synthesis rates in older adults based on wheat protein
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