Health TrialsbyHealthPanel

Mineral Trioxide Aggregate (MTA) vs Gutta-Percha for Non-Surgical Endodontic Retreatment in Teeth With Apical Lesions

ConditionsPeriapical DiseasesRoot Canal TherapyMineral Trioxide Aggregate (MTA)
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Santiago de Compostela

About this trial

The main objective of this study is to compare the healing rate of periapical lesions after non-surgical endodontic retreatment in teeth obturated with gutta-percha versus those obturated with mineral trioxide aggregate (MTA), with a 12-month follow-up. Secondary objectives include evaluating differences between groups in healing time, postoperative pain, and tooth discoloration.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Mineral trioxide aggregate (MTA) group

    Device

    Root canal obturation performed using mineral trioxide aggregate (MTA) following non-surgical endodontic retreatment. After removal of the previous root canal filling, chemomechanical preparation and irrigation of the root canal system are performed. Calcium hydroxide is used as intracanal medication between visits prior to final obturation with MTA

  • Gutta-percha group

    Device

    Root canal obturation performed using gutta-percha and a resin-based sealer following non-surgical endodontic retreatment. After removal of the previous root canal filling, chemomechanical preparation and irrigation of the root canal system are performed. Calcium hydroxide is used as intracanal medication between visits prior to final obturation with gutta-percha using the continuous wave technique.

Treatment groups

58 Participants
are divided into 2 treatment groups
Group A: Mineral trioxide aggregate (MTA) groupExperimental treatment 1 intervention
Group B: Gutta-percha groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Healing of periapical lesions

Radiographic healing of periapical lesions following non-surgical endodontic retreatment, assessed by standardized periapical radiographs and confirmed by cone beam computed tomography (CBCT) when complete healing is suspected. Two blinded evaluators will assess the radiographic outcomes.

Time frame
Follow-up visits at 3, 6, 9, and 12 months post-treatment.

Secondary outcomes

1

Tooth discoloration

Presence or absence of tooth discoloration, measured using a spectrophotometer before the retreatment and at each follow-up visit.

Time frame
Evaluated at baseline (pre-retreatment) and at 3, 6, 9, and 12 months post-treatment.
2

Postoperative Pain

Assessment of patient-reported postoperative pain using a standardized questionnaire.

Time frame
Perioperative (between appointments), 24 hours postoperative, 48 hours postoperative, 1 week postoperative

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Santiago de Compostela

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: