About this trial
This single-center, split-mouth, randomized controlled clinical trial aims to evaluate the clinical effectiveness of Minimally Invasive Non-Surgical Therapy (MINST) as an adjunct to conventional non-surgical periodontal therapy in patients with Stage III/IV periodontitis. Twenty-three systemically healthy adults presenting with bilateral molar teeth exhibiting periodontal pockets ≥5 mm with bleeding on probing will be enrolled. In each participant, molar teeth will be randomly allocated to receive either conventional subgingival scaling and root planing (SRP) using ultrasonic instruments alone (control) or conventional SRP followed by MINST using Mini-Five Gracey curettes under magnification loupes (test). Clinical periodontal parameters, including Plaque Index (PI), Gingival Index (GI), Bleeding on Probing (BOP), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL), will be evaluated at baseline, 3 months, and 6 months after treatment. The study will investigate whether MINST provides superior clinical outcomes compared with conventional non-surgical periodontal therapy.
Eligibility criteria
Qualifiers
Adults aged 18 to 35 years.
Diagnosed with Stage III or Stage IV periodontitis.
Systemically healthy.
Presence of at least two bilateral molar teeth with probing pocket depth (PPD) ≥5 mm and bleeding on probing (BOP).
Disqualifiers
Individuals who do not meet the inclusion criteria.
Pregnancy or breastfeeding.
Presence of systemic diseases or medical conditions affecting periodontal status or healing.
Current use of medications that may influence periodontal healing.
Trial design
Treatments tested in this trial
- Minimally Invasive Non-Surgical Therapy (MINST)
- Conventional Scaling and Root Planing