Mitochondrial Energy Metabolism in Burns
ConditionBurn Injury
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age2-80
SponsorArkansas Children's Hospital Research Institute
About this trial
The goal of this observational study is to assess the impact of burn injury on cellular energetics in patients that have been admitted to the burn center at Arkansas Children's Hospital for burn care and require one or more procedures to clean, debride, and repair burn wounds will be eligible to participate in this study.
During the study, we will collect the following information:
* General background information such as date of birth, height, weight, and other basic information. * Medical information, such as: basic medical information, details of burn injury, vital signs on the day of surgery, medicines you take during your stay, and some clinical tests. * Blood, urine, and tissue during surgeries you have during your stay.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Male or Female
Ages 2 years to 80 years
Requiring hospital admission for burn care
All races
Disqualifiers
Age < 2 years
Under 10 kg in body mass
Age > 80 years
Active pregnancy
Trial population
Up to 125 patients (2 years to 80 years old) will be enrolled in this study. We will recruit both males and females requiring hospital admission to the ACH burn unit for burn care.
Trial design
Design model
Case-only
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Blood Bioenergetics
Peripheral Blood Mononuclear Cell (PBMC) respiration
Time frame
Through study completion, an average of 1 yearSecondary outcomes
1
Blood metabolics signatures
Peripheral Blood Mononuclear Cell (PBMC) respiration
Time frame
Through study completion, an average of 1 yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
Arkansas Children's Hospital Research Institute
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
Collaborator
Source ClinicalTrials.gov