The purpose of this study is to describe the population pharmacokinetic characteristics in patients with suspected/confirmed spinal infections who are undergoing anti-infective drug therapy, and to evaluate effectiveness and safety of these drugs.
Patients with suspected/confirmed spinal infections who are undergoing anti-infective drug therapy.
Pregnant/lactating women.
There are other factors that the researchers think are not suitable for inclusion
Patients with suspected/confirmed spinal infections who are undergoing anti-infective drug therapy.
Cohort
Prospective
Anti-Infective Drugs
DrugAnti-infective drugs are administered using the traditional clinical dosing regimen, with no interventions.
Clearance (L/h)
Volume of Distribution (L)
the ratio of the area under the concentration-time curve from 0 to 24 hours
For time-dependent antimicrobials, the PD target is defined as the time of free drug concentration beyond MIC during the dose interval. For concentration-dependent antimicrobials, the PD target is defined as the ratio of the area under the concentration-time curve from 0 to 24 hours to the MIC.
erythrocyte sedimentation rate
Clinical treatment outcome
Adverse events
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Shandong University
Lead sponsor
Shandong Public Health Clinical Center
Collaborator
