Moisturization and Skin Hydration Study
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-18
SponsorUniversity of British Columbia
About this trial
Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:
* Which moisturization technique is preferred: while showering/bathing or after towel drying? * How do these techniques affect investigator-assessed eczema severity, patient-reported itch scores, and objective skin hydration measurements?
Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.
Participants will:
* Apply moisturizer while showering/bathing for one month and after towel drying for one month. * Complete questionnaires on moisturization technique, skin feel, and itchiness. * Undergo skin hydration measurements using a Corneometer® CM825 device.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Participants must have a diagnosis of atopic dermatitis/eczema.
Participants must be between the age of 12-18.
Participants must be able to bathe independently.
Participants will be English speaking and able to complete questionnaires.
Disqualifiers
Participants who use topical corticosteroids between one inch above the wrist and 1 inch below the elbow from 1 month on both arms prior to the study until the final visit.
Participants who have a known allergy to the moisturizer cream (Cerave Moisturizing Cream) provided.
Trial design
Design model
Crossover
Treatments tested in this trial
Moisturizing while in shower/bath
BehavioralApplying moisturizer in the shower/bath.
Moisturizing after towel drying
BehavioralApplying moisturizer out of the shower/bath after towel drying.
Treatment groups
30 Participants
are divided into 2 treatment groupsGroup A: Moisturizing while in shower/bathExperimental treatment 1 intervention
Group B: Moisturizing after towel dryingExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Proportion of Participants Preferring Each Moisturization Technique
Participant reported preference of moisturization technique
Time frame
Through study completion, an average of 2 months.Secondary outcomes
1
Skin Hydration Level
Skin electrical capacitance measured using Corneometer® CM825 as an indicator of skin hydration.
Time frame
Through study completion, an average of 2 months.Other outcomes
1
Eczema Severity Score
Eczema severity will be assessed by clinicians using the Validated Investigator Global Assessment Scale for Atopic Dermatitis (vIGA-AD™). Scores range from 1 to 4, with higher scores indicating more severe eczema/atopic dermatitis (worse outcome).
Time frame
Through study completion, an average of 2 months.2
Itch Intensity
Itch intensity will be assessed using a patient-reported Numeric Rating Scale (NRS) ranging from 1 to 10, where higher scores indicate greater itch severity (worse outcome). Participants will report both average itch and worst itch experienced within the past 24 hours.
Time frame
Through study completion, an average of 2 months.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
University of British Columbia
Lead sponsor
L'Oreal
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: