Molecular Analysis of Suspected or High-Risk Lung Cancer to Drive Individualized Care
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMayo Clinic
About this trial
This study evaluates the effectiveness of tumor samples in providing information about hereditary or cancer specific genetic variants that may have a role in diagnosis of cancer and to develop genetic results and medical record databank for future studies.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Subject age 18 years and older
Subject is scheduled/was scheduled for a bronchoscopy or surgical resection as part of standard of care
Subject with a moderate to high risk of lung cancer based on clinical demographic and radiologic information or with suspected metastatic disease
Ability to provide blood or saliva sample
Disqualifiers
Individuals who have situations that would limit compliance with the study requirements
Institutionalized (i.e. federal medical prison)
Pregnant
Prior germline genetic testing with a 40+ multi-gene panel AND/OR prior somatic tissue (250+ gene) testing utilizing the tissue from the bronchoscopy or surgical resection
Trial population
Patients scheduled for a bronchoscopy recruited through Mayo Clinic
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Non-Interventional Study
Other interventionNon-interventional study
Treatment groups
250 Participants
are divided into 1 treatment groupGroup A: Observational1 intervention
Trial outcomes
Primary outcomes
1
Percent of samples adequate for sequencing
Assessed based on the number of tissue samples determined to be adequate for WES (Whole Exome Sequencing)/WT (wild-type) sequencing.
Time frame
Up to 2 yearsSecondary outcomes
1
Data bank of genomic data
A data bank of genomic data will be developed for future analyses.
Time frame
Up to 2 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov