About this trial
Investigators use a genome-wide approach within a case-control design to identify SNPs that show evidence of association with lung cancer risk and survival.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
younger than 18 years old
Trial population
Lung cancer cases are recruited from Massachusetts General Hospital patient population. Cases come from Thoracic Surgery or Cancer Center. Healthy controls are no longer recruited.
Trial design
Case-only
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Survival among patients at different stages of lung cancer and treatment will be measured using questionnaires along with medical chart data to monitor treatment and disease progression
Study lung cancer development in a case control study. We will look at three separate outcome measures specified below
Secondary outcomes
Overall survival
Measurement from time of diagnosis to death will be obtained
Progression-free survival
Time of diagnosis to disease progression (measured by metastasis)
Treatment toxicities
Effects on ECOG and physical sequelae from treatment (radiation, chemotherapy and other treatment modalities will be analyzed)
Sponsors and contacts
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Massachusetts General Hospital
Lead sponsor
National Cancer Institute (NCI)
Collaborator