Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNational Taiwan University Hospital

About this trial

The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a protocol of management of elevated ICP and insufficient CPP in post-arrest care, to establish a protocol for personalizing CPP and MAP optimization, and to analyze its impact on neuroprognosis.

Participants will receive ICP monitoring within 12 hours post-ROSC if meet all inclusion and exclusion criteria.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

non-traumatic cardiac arrest

admitted to ICU

GCS: motor <=5

severity: TIMECARD score medium-risk group

Disqualifiers

traumatic cardiac arrest

pregnancy

intracranial hemorrhage

coagulopathy

Trial design

Design model

Single group

Treatments tested in this trial

  • ICP monitoring

    Device

    ICP monitoring

Treatment groups

50 Participants
are divided into 1 treatment group
Group A: ICP monitoringExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

ICP difference between different temperature

Time frame
12 hour, day 1, 3, 7 post-ROSC

Secondary outcomes

1

Difference between direct and non-invasive ICP monitoring indicators

Time frame
12 hour, day 1, 3, 7 post-ROSC

Other outcomes

Sponsors and contacts

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