About this trial
Loss of upper extremity and particularly hand function after stroke reduces independence in daily activities such as eating, dressing, and personal care. Robot-assisted hand rehabilitation provides repetitive, intensive, and task-oriented practice that supports motor learning, dexterity, and functional hand use. Motor imagery, the mental rehearsal of a movement without physically performing it, is thought to activate motor-related brain networks and to support motor learning and neuroplasticity. Evidence on the added value of combining motor imagery with robot-assisted hand rehabilitation for activities of daily living is limited. This randomized controlled trial will investigate whether motor imagery training added to robot-assisted hand rehabilitation produces greater improvement in activities of daily living than robot-assisted hand rehabilitation alone in individuals with stroke. Forty participants will be randomly allocated to an experimental group (robot-assisted hand rehabilitation plus motor imagery, n=20) or a control group (robot-assisted hand rehabilitation alone, n=20). Both groups will receive the same dose of robot-assisted hand rehabilitation with a soft robotic hand rehabilitation glove, three days per week for six weeks. Outcomes will be assessed at baseline and after the six-week program.
Eligibility criteria
Qualifiers
Aged 18 years or older
Diagnosis of stroke
Impairment of upper extremity function, particularly hand function
Modified Ashworth Scale grade of 2 or below in the wrist and finger flexors
Disqualifiers
Severe cognitive, visual, or hearing impairment
Additional neurological or orthopaedic disease affecting the upper extremity
Modified Ashworth Scale grade above 2 in the wrist and finger flexors
Marked contracture, advanced joint restriction, or pain preventing the intervention
Trial design
Treatments tested in this trial
- Robot-assisted hand rehabilitation
- Motor imagery training