Mouth Odor on Preventing Pneumonia by Oral Frailty
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorNational Cheng-Kung University Hospital
About this trial
This research plan aims to first collect data on the oral function and oral hygiene status of the elderly population in the community and to understand the normal model of oral frailty among the older adults in the community. Subsequently, a comparison will be made between the oral status of hospitalized patients and the community-dwelling elderly population. The goal is to verify whether oral odor can be used as an objective biological indicator following intervention.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥ 50 years old,
Alert and oriented,
With sufficient comprehension and cooperation,
Willing to participate in oral assessment.
Disqualifiers
Patients who score below 5 on the General Practitioner Assessment of Cognition (GPCOG),
Patients with oral treatments such as oral cancer treatment,
Patients with oral treatments such as periodontal disease treatment.
Trial design
Design model
Parallel
Treatments tested in this trial
Oral exercises and oral hygiene
Procedure/SurgeryThe patients will be required to perform oral exercises and maintain oral hygiene twice a day. The investigators will assess their oral frailty, oral bacteria, oral odor, and other related clinical care data on the following time points: day 1 of hospitalization, day 3 of hospitalization, the day of discharge, one week after discharge, and one month after discharge.
Oral care
Procedure/SurgeryThe patients will be required to maintain oral hygiene twice a day. The investigators will assess their oral frailty, oral bacteria, oral odor, and other related clinical care data on the following time points: day 1 of hospitalization, day 3 of hospitalization, the day of discharge, one week after discharge, and one month after discharge.
Treatment groups
304 Participants
are divided into 3 treatment groupsGroup A: Group with oral managementExperimental treatment 1 intervention
Group B: Group with oral careExperimental treatment 1 intervention
Group C: Group with standard of careNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Clearance of pneumonia associated oral bacteria
The investigators collected tongue specimens from participants for bacterial isolation and identification. The participants' specimens were collected using an eswab and sent for bacterial culture within 2 hours. Bacterial colonies were quantified (CFU/ml). To observe the variation caused by the number of bacteria, measurements were taken again after the intervention. The investigators assessed the clearance of bacteria based on the baseline.
Time frame
The first day of admission (baseline)2
Clearance of pneumonia associated oral bacteria
The investigators collected tongue specimens from participants for bacterial isolation and identification. The participants' specimens were collected using an eswab and sent for bacterial culture within 2 hours. Bacterial colonies were quantified (CFU/ml). To observe the variation caused by the number of bacteria, measurements were taken again after the intervention. The investigators assessed the clearance of bacteria based on the baseline.
Time frame
Day 3 of admission3
Clearance of pneumonia associated oral bacteria
The investigators collected tongue specimens from participants for bacterial isolation and identification. The participants' specimens were collected using an eswab and sent for bacterial culture within 2 hours. Bacterial colonies were quantified (CFU/ml). To observe the variation caused by the number of bacteria, measurements were taken again after the intervention. The investigators assessed the clearance of bacteria based on the baseline.
Time frame
Discharge day4
Clearance of pneumonia associated oral bacteria
The investigators collected tongue specimens from participants for bacterial isolation and identification. The participants' specimens were collected using an eswab and sent for bacterial culture within 2 hours. Bacterial colonies were quantified (CFU/ml). To observe the variation caused by the number of bacteria, measurements were taken again after the intervention. The investigators assessed the clearance of bacteria based on the baseline.
Time frame
1-week after discharge daySponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov