Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-85
SponsorUniversity of Portsmouth
About this trial
This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Diagnosed symptomatic bilateral or unilateral knee osteoarthritis, self-reported ability to walk without an aid for 10 minutes and to ascend and descend stairs, no neurological conditions or other musculoskeletal pathology/injury which would impact walking gait.
Disqualifiers
Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking, lacking ability to consent.
Trial population
Local private physiotherapy clinics and local sports clubs
Trial design
Design model
Case-crossover
Time perspective
Cross-sectional
Treatments tested in this trial
No intervention
Other interventionObservational cross-sectional study
Treatment groups
36 Participants
are divided into 3 treatment groupsGroup A: Total Knee Replacement1 intervention
Group B: Knee Osteoarthritis1 intervention
Group C: Asymptomatic Controls1 intervention
Trial outcomes
Primary outcomes
1
Peak knee adduction moment
The external knee adduction moment (KAM), which reflects medial-to-lateral knee joint load distribution during gait, has become an OA treatment target. The peak KAM is a strong predictor of presence, severity, and the rate of progression of knee OA.
Time frame
From the start of a biomechanical movement testing visit to the end (approximately 2 hours)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov