MRI Analysis and Degenerative Spine
ConditionSpine Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-85
SponsorUniversidade Nova de Lisboa
About this trial
Analysis of MRI advanced techniques in degenerative spinal disease.
The main questions it aims to answer are:
* Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease * What are the image biomarkers affected by disease * How they evolve with disease progression and treatment
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age between 50 and 85 years
Diagnosis of spinal disease by clinical and imagiological criteria
More than 3 months duration of disease
Ability to give consent
Disqualifiers
Previous spine surgery
Spinal instability
Neurological disease that might interfere with walking
Known orthopedic conditions that causes significant gait impairment
Trial population
Patients with suspected diagnosis of the spinal disease in study and that meet the eligibility criteria.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
MRI advanced techniques
Diagnostic testParticipants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.
Treatment groups
200 Participants
are divided into 2 treatment groupsGroup A: Control1 intervention
Group B: Disease1 intervention
Trial outcomes
Primary outcomes
1
ODI - Oswestry Disability Index
Measured using the ODI scale (range 0 - 50)
Time frame
18 months2
Lumbar Pain Intensity
Measured using the Numeric Pain Rating Scale (range: 0 - 10 )
Time frame
18 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov