Multi-agent LLMs for Decision Support in Cervical Cancer During Pregnancy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeNot listed
SponsorObstetrics & Gynecology Hospital of Fudan University

About this trial

The aim of this study is to develop an AI-assisted decision-making system based on multi-agent large language models and to evaluate its effectiveness and accuracy in the diagnosis and treatment of cervical cancer during pregnancy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Pathologically confirmed diagnosis of cervical cancer.

Confirmed intrauterine pregnancy status via ultrasound.

Patients receiving initial treatment.

Agreement to participate in the study with signed informed consent.

Disqualifiers

Previous treatment received for cervical cancer during pregnancy.

Pathological pregnancy states (e.g., ectopic pregnancy).

Inability or unwillingness to provide signed informed consent.

Trial design

Design model

Parallel

Treatments tested in this trial

  • multi-disciplinary agents group

    Other intervention

    generate diagnosis and treatment opinions for each case from multi-disciplinary agents

  • real MDT group

    Other intervention

    generate diagnosis and treatment opinions for each case from a real MDT team inclduing senior physicians from relevant departments, including gynecologic oncology, pediatrics, obstetrics, medical oncology and radiation oncology.

  • junor doctor group

    Other intervention

    generate diagnosis and treatment opinions for each case from junior doctor who are residents from relevant departments, including gynecologic oncology, pediatrics, obstetrics, medical oncology and radiation oncology.

  • junor doctor group with aid of MDT agents

    Other intervention

    generate diagnosis and treatment opinions for each case from junior doctor who are residents from relevant departments, including gynecologic oncology, pediatrics, obstetrics, medical oncology and radiation oncology after referring to the results from MDT agent .

Treatment groups

150 Participants
are divided into 2 treatment groups
Group A: Arm1: multi-disciplinary agents groupExperimental treatment 1 intervention
Group B: Arm2: real MDT group/ junior doctors group/junior doctors after referring to agent results groupPlacebo comparator 3 interventions

Trial outcomes

Primary outcomes

1

Accuracy of the MDT decision

scores, from 0 to 100, accuracy of the MDT decision according to evaluation indicators of each discipline

Time frame
immediately after the intervention

Secondary outcomes

1

Consuming time

seconds, consuming time for generating MDT decisions from MDT agents/ real MDT team

Time frame
immediately after the intervention

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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