Multi-Field-Strength MRI Brain Atlas Construction in Healthy Chinese Population

ConditionHealthy Adult Brain Imaging

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age16-66

SponsorTang-Du Hospital

About this trial

This prospective imaging study aims to construct a multi-field-strength magnetic resonance imaging (MRI) brain atlas for healthy Chinese adults. Healthy volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths, including 0.55T, 1.5T, 3T, 5T, and 7T. Structural, diffusion, functional, and other quantitative MRI data will be acquired and analyzed. The study will characterize the consistency and differences in brain morphology and imaging measurements across field strengths and establish standardized multi-field-strength brain templates and reference data for healthy Chinese adults.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Aged 16 to 66 years. Voluntarily participates in the study and provides written informed consent. No contraindications to MRI examination and able to cooperate with and complete the MRI examinations.

Disqualifiers

Presence of contraindications to MRI examination, including MRI-incompatible implanted metallic or electronic devices, cochlear implants, cardiac pacemakers, intracranial metallic clips, or similar devices.

Trial design

Design model

Single group

Treatments tested in this trial

Multi-Field-Strength Brain MRI
Diagnostic test
Participants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T. MRI acquisitions include structural, diffusion, functional, and quantitative imaging sequences according to the study protocol. No therapeutic intervention will be administered

Treatment groups

500 Participants

are divided into 1 treatment group

Group A: Healthy Chinese AdultsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Regional Gray Matter Volume Across MRI Field Strengths

Regional gray matter volumes will be quantified from standardized structural MRI data and compared across 0.55T, 1.5T, 3T, 5T, and 7T MRI acquisitions.

Time frame

From enrollment through completion of all scheduled multi-field-strength MRI examinations, up to 12 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tang-Du Hospital

Lead sponsor

Xi'an Jiaotong University

Collaborator

Source ClinicalTrials.gov

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