The goal of this clinical trial is to evaluate the clinical effects of ultra-fast-track anesthesia (UFTA) for minimally invasive cardiac surgery (MICS) in adults. It will also learn about the safety and feasibility of Ultra-Fast-Track cardiac surgery(UFTCA).The main questions it aims to answer are:Does UFTCA promote rapid postoperative recovery, reduce postoperative complications and perioperative mortality, and improve the quality of mid- and long-term survival.And does it improve patient satisfaction and reduce healthcare costs.
Participants will receive homogenized perioperative management in the cardiac ward, extracorporeal circulation, and postoperative ICU, except for anesthesia extubation time.Furthermore，Participants need complete quality of life scales at 30 days, 90 days, six months, and one year after surgery, separately.
Participants in this study are adults who required elective minimally invasive heart valve surgery under extracorporeal circulation.This study will be able to promote rapid recovery while reducing the associated costs and the financial burden on participants.Retrospective big data analysis of perioperative clinical characteristics of patients undergoing minimally invasive heart valve surgery to establish a risk warning model and develop a perioperative management program. The investigators then conducts a randomized group trial comparing the similarities and differences between conventional general anesthesia（CGA） and ultra-fast-track cardiac anesthesia(URTCA) to demonstrate the effectiveness and safety of UFTA in MICS.Finally, building expert consensus.
Age ≥18 and ≤80 years
American Society of Anaesthesiologists (ASA) class I-III
New York Heart Association (NYHA) cardiac class III or below
Preoperative inspired air pulse oximetry (SpO2) ≥95%
Patient's refusal to participate
Severe communication disorders
Severe disorders of coagulation with spontaneous bleeding tendency
Long-term application of opioid analgesics
Parallel
Ultra-Fast-Track Cardiac Anesthesia(UFTCA)
Procedure/Surgery(UFTCA)The researcher removed the endotracheal tube either immediately or within 1 hour of the end of the procedure.
conventional general anesthesia (CGA)
Procedure/Surgery(CGA)The researcher not extubated at the end of the operation and were admitted to the ICU under anesthesia with an endotracheal tube.
tracheal tube extubation time
Time interval for tracheal extubation
ICU length of stay
Length of time participants stayed in the ICU
Post-operative hospitalization
Length of postoperative hospitalization
Length of hospitalization
Length of time participants stayed in the hospital
Time from end of surgery to removal from operating room
Time from end of surgery to removal from operating room
Intraoperative opioid dosages
Intraoperative dosage of sufentanil and remifentanil for induction and maintenance of anesthesia
VAS score
minimum values:1 maximum values:10 higher scores mean a worse outcome
Postoperative opioid dosage
Level of postoperative analgesia
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Zhejiang Provincial People's Hospital
Lead sponsor
Beijing Anzhen Hospital
Collaborator
Fudan University
Collaborator
Wuhan Asia Heart Hospital
Collaborator
Tianjin Chest Hospital
Collaborator
Chinese PLA General Hospital
Collaborator
First Affiliated Hospital Xi'an Jiaotong University
Collaborator
Xiangya Hospital of Central South University
Collaborator
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Collaborator
Guangdong Provincial People's Hospital
Collaborator
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