Multicentre Evaluation of Spinal Bone Pathologies Using Zero Echo Time (ZTE) Pseudo-CT MRI Sequences: a Clinical Implementation Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain

About this trial

Innovative sequences known as "pseudo-CT"-such as Ultrashort Echo Time (UTE) and Zero Echo Time (ZTE)-enable good visualization of mineralized bone. These new sequences appear to enhance MRI performance in the detection of fractures, spondylolysis, and other bone abnormalities.

We would like to offer patients referred for a CT scan due to lumbar spine bone pathology the option of undergoing an MRI study, in order to compare the performance of the two techniques.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults requiring a CT scan as part of their clinical assessment for lumbar spine imaging who also provide informed consent to participate in the study.

Patients presenting with acute or chronic low back pain and requiring a CT scan for diagnostic purposes.

Disqualifiers

Contraindications to MRI, such as pacemakers, metal implants, severe claustrophobia, or pregnancy

Spinal surgery within the last six months.

Patients who cannot or do not wish to provide informed consent.

Trial design

Design model

Single group

Treatments tested in this trial

  • MRI

    Device

    Lumbar spine MRI using innovative sequences known as "pseudo-CT," enabling the capture of signals from tissues with very short T2 relaxation times and providing good visualization of mineralized bone.

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: All patientsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

sensitivity and specificity of pseudo-CT MRI

To evaluate the sensitivity and specificity of pseudo-CT MRI for the detection of bone lesions.

Time frame
One MRI of 30 min

Secondary outcomes

Other outcomes

Sponsors and contacts

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