Multicomponent Training and Muscle Quality in Older Women

ConditionSarcopenia

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexFemale

Age60+

SponsorUniversity of Salamanca

About this trial

This study aims to evlauate the effect os a 32-week multicomponent training (MT) program on muscle architecture and muscle quality (assessed by ultrasound) in womer over 60 years. The study will also analyze concurrent changes in muscle strength, physical performance, and body composition. The hypothesis is that the training will induce positive architectural adaptations, such as reduced echogenicity and increased thickness in the rectus femoris and rectus abdominis muscles, correlating with improved functional independence.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Being a woman over 60 years of age, residing in the community, and enrolled in the GPR

Disqualifiers

Having neuromuscular diseases, recent abdominal surgery, metal implants incompatible with measurements, unstable cardiovascular diseases, or previous participation in another exercise program.

Trial design

Design model

Parallel

Treatments tested in this trial

Multicomponent training
Other intervention
The exercise battery includes lower body work (squats, deadlifts, front and sagittal plane lunges, hip abduction/extension, and plantar flexion) and upper body work (wall flexion-extensions, shoulder raises, and elbow flexion-extensions). In addition to the strength exercises mentioned above, balance exercises such as walking in tandem, standing on one leg, side steps, and weight transfer will also be performed. Aerobic capacity will be worked on by walking at a moderate intensity, and flexibility will be improved through stretching the main muscle groups.

Treatment groups

40 Participants

are divided into 2 treatment groups

Group A: Intervention Group (Multicomponent training)Experimental treatment 1 intervention

Group B: Control GroupNo intervention 0 interventions

Trial outcomes

Primary outcomes

Echo intensity

Echo intensity (gray scale analysis), using ImageJ software, proposed by the SARCUS consensus and Nutritional Ultrasound ®.

Time frame

Baseline and 32 weeks

Muscle thickness (mm)

Linear measurement of the distance between the superficial and deep aponeuroses of a target muscle belly.

Time frame

Baseline and 32 weeks

Cross-sectional area

The total area of the muscle (measured in cm\^2) in a plane perpendicular to its longitudinal axis

Time frame

Baseline and 32 weeks

Subcutaneous adipose tissue thickness

Measurement of the distance between the dermis and the superficial muscle fascia. This variable quantifies the thickness of the fat layer located directly beneath the skin.

Time frame

Baseline and 32 weeks

Secondary outcomes

Handgrip strength (kg)

Handgrip strength will be assessed using dynamometry due to its association with various outcomes of aging, being a key component in sarcopenia and frailty. Measurements will be taken using the Hydraulic Jamar device with the subject standing and the elbow flexed at 90º.

Time frame

Baseline and 32 weeks

Short Physical Performance Battery (SPPB)

The Short Physical Performance Battery (SPPB) will be used, a quick and objective three-part physical function test with excellent test-retest reliability, predictive validity, and clinical applicability, mainly used for fall risk stratification.

Time frame

Baseline and 32 weeks

Timed Up and Go (TUG)

The Timed Up and Go (TUG) test will be used as it is a valid tool for detecting balance deficits, which are associated with an increased risk of falls in older adults.

Time frame

Baseline and 32 weeks

5-time sit-to-stand (5STS)

The 5-time sit-to-stand (5STS) test will be used, a functional test serves to assess lower limb strength.

Time frame

Baseline and 32 weeks

Other outcomes

Sociodemographic variables

Personal data, medical history, presence of comorbidities, use of medications will be collected in a personal interview, and finally, blood pressure will be taken.

Time frame

Baseline and 32 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Salamanca

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: