About this trial
The primary aim of this study is to evaluate the effectiveness of multimodal brain monitoring technologies as both an early warning system and a prognostic tool in patients suffering from acute brain injuries. This research seeks to determine how effectively these tools can predict clinical outcomes and prevent complications by providing early alerts to healthcare professionals.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Must be 18 years of age or older.
Diagnosed with Traumatic Brain Injury (TBI) or has suffered from acute brain injury due to intracranial hemorrhage or subarachnoid hemorrhage.
Defined as an admission Glasgow Coma Scale (GCS) Eye Response score of 1 (unable to open eyes) and a GCS Motor Response score of ≤5 (unable to obey commands).
Occurs within 48 hours of admission, where the patient does not open eyes and motor score drops to 5 or below.
Disqualifiers
Patients who were not admitted to the Intensive Care Unit (ICU) are excluded.
Patients with forms of acute brain injury other than those specified (TBI, intracranial hemorrhage, subarachnoid hemorrhage) are also excluded.
Patients with known severe liver or kidney dysfunction are excluded.
Patients whose vital signs are extremely unstable after admission, with a very poor prognosis and considered unable to survive, and whose family has decided to forgo further treatment.
Trial population
Critically Ill, Acute Brain Injury Adult Patients.
Trial design
Cohort
Retrospective
Treatments tested in this trial
no intervention
Other interventionno intervention
Treatment groups
Trial outcomes
Primary outcomes
Relation between multimodal brain monitoring parameters and outcome.
Association between advanced multimodal brain monitoring parameters of the first 48h of admission and six months functional outcome (Glasgow Outcome Score Extended)
Secondary outcomes
Neuromonitoring Pattern
Describe multimodal neuromonitoring parameters variation and identify trends.
Neuromonitoring and Short Term Outcome
Association between advanced multimodal brain monitoring parameters and 28 days functional outcome (Glasgow Outcome Score Extended)
Locations
Sponsors and contacts
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