Multimodal Imaging Evaluation and Prognostic Analysis of Participants After Arterial Switch Operation

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorXie Mingxing

About this trial

The aims of this study are to

1. Identify the early and midterm outcomes in terms of mortality and reoperation of the arterial switch operation (ASO). 2. Identifying the influence of coronary artery anomalies on the in-hospital and post-discharge prognosis after ASO. 3. Evaluate the predictors for neoaortic valve regurgitation after ASO. 4. Explore the risk factors for neopulmonary artery stenosis after ASO.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patients with various forms of TGA undergoing Réparation à l'Etage Ventriculaire procedure

Patients with various forms of TGA undergoing Rastelli procedure

Patients with various forms of TGA undergoing Nikaidoh procedure

Patients with various forms of TGA undergoing Fontan operation

Trial population

All participants diagnosed with TGA or TBA underwent ASO in the hospital with an eligible cardiovascular surgery center.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

1,000 Participants
are grouped into 1 trial group
Group A: ASO group

Trial outcomes

Primary outcomes

1

All cause mortality

Number of participants with all cause mortality after ASO

Time frame
Ten years

Secondary outcomes

1

Cardiac caused mortality

Number of participants with cardiac caused mortality after ASO

Time frame
Ten years
2

All cause reoperation

Number of participants with all cause reoperation after ASO

Time frame
Ten years
3

Right-ventricular outflow tract obstruction and pulmonary branch stenosis

Degree of more than moderate right-ventricular outflow tract obstruction in millimetre of mercury, degree of pulmonary branch stenosis in millimetre of mercury

Time frame
Ten years
4

Neoaortic valve regurgitation

Vena contracta width of neoaortic valve regurgitation in milimetre, ratio of Jet width/LVOT width in percentage

Time frame
Ten years

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Xie Mingxing

Lead sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Sponsor institution

Second Affiliated Hospital, School of Medicine, Zhejiang University

Collaborator

Shanghai Zhongshan Hospital

Collaborator

Henan Provincial People's Hospital

Collaborator

Wuhan Asia Heart Hospital

Collaborator

Guangdong Provincial People's Hospital

Collaborator

This trial is not recruiting at the moment. You can still explore other options: