About this trial
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy and unhealthy individuals.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
for CLTI patients age >50
for age control group age >50 and not diagnosed with cardiovascular diseases. 0.9 < ABI < 1.3
for healthy group 18 <= age <= 50 and no history of cardiovascular disease
volunteering for study
Disqualifiers
inability to give informed consent
denial
Trial population
* patients at the Vascular Centre Polyclinic and Vascular Surgery Ward at Tampere University Hospital * Orthopaedic patients, joint replacement hospital and orthopaedic ward at Tampere University Hospital * students and staff from Tampere University and Tampere University Hospital
Trial design
Case-control
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Perfusion in lower limb angiosomes assessed by thermal imaging
Thermal imaging will be used to assess the perfusion in the lower limbs. The lower limb can be divided into six angiosomes, which can then be used to assess thermal patterns. Healthy and unhealthy feet will present with different thermal patterns and other changes in thermographs.
Oxygenation in lower limb angiosomes assessed by hyperspectral imaging.
Hyperspectral imaging can be used in the assessment of oxygenation in the lower limb angiosomes. Based on hyperspectral imaging, oxygenation maps can be generated and then analyzed. Differences between the oxygenation maps of healthy and unhealthy patients will be established.
Sponsors and contacts
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Tampere University
Lead sponsor
Tampere University Hospital
Collaborator