Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire, Amiens

About this trial

The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials. The proposed treatments are based on surgery, physiotherapy and botulinum toxin injections. However, when recovery is incomplete, acceptance is more difficult, with an impacted quality of life. Thanks to Motion Capture and Electromyography, a quantification of the facial mimicry is now possible with a great precision. In addition with the quantification of the facial mimicry, eye-tracking, wich is widely used in the marketing field, but it also finds medical applications including head and neck lesions and facial palsy in particular, will be used to evaluate the visio of the patients on their pathology in function of the movement quantification measured with MoCap and Electromyography. The aim of this research is to measure in a combined way the action potentials by sEMG and the amplitudes of displacement of the markers in motion capture, for movements determined in a population of patients presenting a facial pathology, in order to compare them with reference values obtained in healthy subjects. In a second step, the aim will be to study if there is a link between the way the patient looks at his pathology and the results of his management (treatment, rehabilitation) which will be quantitatively evaluated thanks to MoCap and sEMG.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Subjects with no known facial pathology (healthy volunteers) OR

Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated

Subject with written informed consent

Subject over 18 years of age

Disqualifiers

Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers

Subjects with speech disorders making it impossible to pronounce the sounds [o] and [pu]

Subject unable to provide written informed consent

Subjects under guardianship, curators or safeguard of justice

Trial design

Design model

Parallel

Treatments tested in this trial

  • dental impressions

    Other intervention

    dental impressions

  • Simultaneous MoCap and EMG acquisition

    Other intervention

    Simultaneous MoCap and EMG acquisition

  • Eye-tracking acquisition for pathological subjects

    Other intervention

    Eye-tracking acquisition for pathological subjects

  • Follow-up visit for pathological subjects

    Other intervention

    Follow-up visit for pathological subjects

Treatment groups

720 Participants
are divided into 2 treatment groups
Group A: patients with facial palsyExperimental treatment 4 interventions
Group B: healthy volunteersActive comparator 2 interventions

Trial outcomes

Primary outcomes

1

determination of baseline values of facial mimicry (in millimetres) in healthy volunteers

determination of baseline values of facial mimicry (in millimetres) in healthy volunteers

Time frame
one month
2

determination of baseline values of eye-tracking (in millimetres) in healthy volunteers

determination of baseline values of eye-tracking (in millimetres) in healthy volunteers

Time frame
one month
3

determination of the maximum range of motion of facial mimicry (in millimetres) in patients

determination of the maximum range of motion facial mimicry (in millimetres) in patients

Time frame
one year
4

determination of the maximum range of motion of eye-tracking (in millimetres) in patients

determination of the maximum range of motion of eye-tracking (in millimetres) in patients

Time frame
one year

Secondary outcomes

Other outcomes

Sponsors and contacts

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