Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

About this trial

The Brain Cancer Program, in partnership with the Center for Music and Medicine at Johns Hopkins, will study whether music therapy is feasible in newly diagnosed GBM patients undergoing standard care.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Glioblastoma (Newly Diagnosed)

Cognitive capacity to respond to surveys

Access to computer and web access

Ability to attend virtual music therapy sessions

Disqualifiers

Not planning to undergo standard of care radiation therapy and concurrent and adjuvant temozolomide.

A life expectancy of less than 6 months.

Concurrent use of any other standard or investigational agents (excepting tumor treating fields).

Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection or psychiatric illness/social situations that would limit adherence with study requirements.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Music intervention

    Other intervention

    Each GBM study participant in Arm A will receive two 30-minute live synchronous virtual music therapy sessions per week for a period of 8 weeks to be curated by a board-certified music therapist. Arm B participants will receive curated playlists of music created by a music therapist. Participants will then listen to the curated music playlists on the participant's own device twice per week. All participants will complete a total of 16 music therapy sessions, scheduled twice per week over 8 weeks. Each session will last approximately 30 minutes.

Treatment groups

35 Participants
are divided into 2 treatment groups
Group A: Arm A- with Music TherapistsExperimental treatment 1 intervention
Group B: Arm B- without Music TherapistsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Success rate of Music Therapy intervention for GBM patients

Determine success rate of the delivery of individualized virtual music therapy (MT) in participants undergoing standard of care treatment for newly diagnosed glioblastoma.

Time frame
6 months

Secondary outcomes

1

Rate of survey completion

Rate of participants completing all surveys.

Time frame
2 years

Other outcomes

Sponsors and contacts

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