Musical Training: Promoting Brain Function in Children Who Have Survived Brain Tumours
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-16
SponsorThe Hong Kong Polytechnic University
About this trial
This study aims to understand whether learning music can help improve brain function and quality of life in children who have recovered from brain tumours. A total of 236 children will join the study. Some of them will receive regular medical care, while others will take part in a music training program using the ukulele. The music program will last for one year and includes both in-person group classes and online individual sessions. The investigators will assess how well the children can think, remember, and focus before and after the training. The investigators will also ask about their daily life and well-being. This study hopes to show that music training can be a fun and helpful way to support recovery in childhood brain tumour survivors.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Completed cancer treatment at least 2 months previously,
Aged 7-16 years,
Able to speak Cantonese and read Chinese
Have had no musical training since their cancer diagnosis
Disqualifiers
Have cancer recurrence or a second malignancy
Trial design
Design model
Parallel
Treatments tested in this trial
Musical Training Program
Other intervention52 weeks of musical training, consisting of (1) 36 weekly group based, face-to-face sessions, and (2) 16 weeks of weekly online individual sessions. Each lasting 45 minutes to 1 hour.
Treatment groups
236 Participants
are divided into 2 treatment groupsGroup A: The intervention group will receive 52 weeks of musical training, including face-to-face and online.Other 1 intervention
Group B: ControlNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Nonverbal Intelligence Score as Measured by the Test of Nonverbal Intelligence, Fourth Edition (TONI-4)
The Test of Nonverbal Intelligence, Fourth Edition (TONI-4) is a language-free measure of nonverbal intelligence, abstract reasoning, and problem-solving.The Index score (mean = 100, SD = 15) will be reported. Higher scores indicate better nonverbal intelligence.
Time frame
At baseline, 12 months immediately after the completion of the intervention, and 6 months after the completion of the intervention2
Digit Span Score (Forward + Backward)
Digit Span (Digits Forward + Digits Backward) assesses attention and working memory. The total score will be reported. Higher scores indicate better attention and working memory performance.
Time frame
At baseline, 12 months immediately after the completion of the intervention, and 6 months after the completion of the intervention3
Memory Score as Measured by the Hong Kong List Learning Test, Second Edition (HKLLT-2)
The Hong Kong List Learning Test, Second Edition (HKLLT-2) assesses verbal memory. The total recall / delayed recall score will be reported. Higher scores indicate better memory performance.
Time frame
At baseline, 12 months immediately after the completion of the intervention, and 6 months after the completion of the intervention4
Processing Speed / Executive Function as Measured by the Children's Color Trails Test (CCTT)
The Children's Color Trails Test (CCTT) assesses sustained attention, sequencing, and executive function. Trail 1 involves connecting numbers (1-15) in sequence, while Trail 2 adds alternating between two colours. Processing speed is estimated from Trail 1 time, while the interference index (Trail 2 minus Trail 1) reflects executive functions, including inhibitory control and cognitive flexibility.
Time frame
At baseline, 12 months immediately after the completion of the intervention, and 6 months after the completion of the interventionSecondary outcomes
1
Quality of life scores of the child participants
Measured by The Chinese version of the Paediatric Quality of Life Inventory (PedsQL)
Time frame
At baseline, 12 months immediately after the completion of the intervention, and 6 months after the completion of the interventionSponsors and contacts
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Source ClinicalTrials.gov
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