Myocardialbridge Bypass Graft Surgery Efficacy Verification

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorXi'an International Medical Center Hospital

About this trial

Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with myocardialbridge requiring drug therapy or surgical intervention.

Disqualifiers

patients with myocardialbridge not requiring drug therapy or surgical intervention, or unwilling to be enrolled for any reason

Trial design

Design model

Parallel

Treatments tested in this trial

  • MBBG

    Procedure/Surgery

    The patients with deep(depth\>2mm) and long-segement(length\>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG),fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.

  • MB CABG

    Procedure/Surgery

    The patients with deep(depth\>2mm) and long-segement(length\>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG),fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The moderate-to-severe atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.

  • MB unroof

    Procedure/Surgery

    The patients with superficial type(depth\<2mm) and short-segement(length\<25mm) of myocardial bridge will be allocated to receive myocardialbridge "unroof" surgery,when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The MB was superficial and short confirmed by coronory artery CT angiography.

Treatment groups

500 Participants
are divided into 3 treatment groups
Group A: MyocardialBridge Bypass GraftExperimental treatment 1 intervention
Group B: Myocardialbridge CABGActive comparator 1 intervention
Group C: Myocardioalbridge UnroofActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

All-Cause Mortality

Time frame
Up to 240 months
2

Rate of counduit patency

Time frame
Up to 180 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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