NASA Exercise Prebreathe Study
ConditionDecompression Sickness
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-60
SponsorDuke University
About this trial
This study evaluates oxygen prebreathe protocols and exercise conditions to reduce risk of decompression sickness during simulated extravehicular activity. Healthy adult volunteers will undergo oxygen prebreathe followed by hypobaric chamber exposure with monitoring for symptoms and ultrasound detection of bubbles.
Eligibility criteria
Qualifiers
Non-smoking volunteers aged 30-60 years
Able to meet VO2 peak requirements (>35 ml/kg/min males, >30 ml/kg/min females)
Disqualifiers
Pregnancy
Lung disease, heart disease, hypertension, or diabetes
Musculoskeletal pain conditions
Requirement for regular medications such as analgesics
Trial design
Treatments tested in this trial
- Oxygen Prebreathe and Hypobaric Exposure
Treatment groups
30 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Duke University
Lead sponsor
National Aeronautics and Space Administration (NASA)
Collaborator
Source ClinicalTrials.gov