Health TrialsbyHealthPanel

Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients

ConditionVentilated Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥ 18 years

Tracheostomy and mechanical ventilation

Dyspnea ≥3

Consent to participate

Disqualifiers

Agitation, delirium

Continuous use of sedatives

Patients under law protection

Inmates

Trial design

Design model

Single group

Treatments tested in this trial

  • Baseline

    Procedure/Surgery

    patient ventilated through the tracheostomy with initial ventilator settings

  • Installation of high flow humidified air cannula

    Procedure/Surgery

    Installation of high flow humidified air cannula with inspired oxygen fraction (FiO2) 21%

  • Nasal air puffs

    Procedure/Surgery

    Nasal air puffs synchronized with the inspiratory time of the ventilator

  • propeller fan (FAN)

    Procedure/Surgery

    Stand-alone fan at the bedside directed toward the face of the patient

Treatment groups

24 Participants
are divided into 1 treatment group
Group A: Patients ventilatedExperimental treatment 4 interventions

Trial outcomes

Primary outcomes

1

Dyspnea

visual analogical scale

Time frame
minute 20

Secondary outcomes

1

airway occlusion pressure

visual analogical scale

Time frame
minute 20
2

end expiratory occlusion pressure

visual analogical scale

Time frame
minute 20
3

respiratory electromyogram (EMG)

visual analogical scale

Time frame
minute 20
4

tolerance

visual analogical scale

Time frame
minute 20

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assistance Publique - Hôpitaux de Paris

Lead sponsor

Source ClinicalTrials.gov
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