The primary aim of the study is to develop a national registry of cerebrovascular diseases in order to define the subtypes of these diseases associated with a worse prognosis. Secondly, the study aims to find clinical, radiological, and biological markers capable tof predicting the outcome of cerebrovascular diseases and the onset of complications related to therapeutic procedures, and to calculate predictive prognostic scores composed of multiple variables.
Each participating center will collect clinical, radiological, and biological data from the medical records of the study participants. Patients included in the study will not undergo any additional medical procedures to those of normal clinical practice.
Diagnosis of cerebrovascular pathology defined according to the NINDS special report of 1990 as "all disorders in which there is an area of the brain transiently or permanently affected by ischemia or bleeding and/or in which one or more blood vessels of the brain are mainly altered by a pathological process", falling within the following codes of the International Classification of Diseases, 9th revision (ICD-9): ICD-9 430-438;
Informed consent provided by the patient or his legal representative in the case of mental incapacity or by the parents/guardians in the case of minors.
The patient, his legal representative in the case of mental incapacity or his parents/guardians in the case of minors clearly state their will to leave the study;
Onset of cerebrovascular disease before January 1, 2016.
All patients with cerebrovascular diseases occuring between January 1, 2016 and July 1, 2049 who consented to partecipate in the study
Cohort
Other
Collection of clinical, radiological, and biological data from patients' medical records
Other interventionCollection of clinical, radiological, and biological data from patients' medical records
Identification of subtypes of each cerebrovascular disease (ICD-9 430-438) associated with poor prognosis.
Identification and definition of the various subtypes of each cerebrovascular disease (International Classification of Diseases, 9th revision (ICD-9): ICD-9 430-438) associated with poor prognosis.
Identification of clinical variables of each cerebrovascular disease correlated with its prognosis
Identification of the clinical variables of each cerebrovascular disease correlated with its prognosis
Identification of radiological variables of each cerebrovascular disease correlated with its prognosis
Identification of the radiological variables of each cerebrovascular disease correlated with its prognosis
Identification of biomarkers of each cerebrovascular disease correlated with its prognosis
Identification of the biomarkers of each cerebrovascular disease correlated with its prognosis
Identification of neurophysiological variables of each cerebrovascular disease correlated with its prognosis
Identification of the neurophysiological variables of each cerebrovascular disease correlated with its prognosis
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead sponsor
Humanitas Hospital, Italy
Collaborator
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Collaborator
IRCCS National Neurological Institute "C. Mondino" Foundation
Collaborator
I.R.C.C.S. Fondazione Santa Lucia
Collaborator
Ospedale Policlinico San Martino
Collaborator
IRCCS San Camillo, Venezia, Italy
Collaborator
Istituto Di Ricerche Farmacologiche Mario Negri
Collaborator
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Collaborator
Ospedale Pediatrico Bambin Gesù
Collaborator
Fondazione IRCCS Policlinico San Matteo di Pavia
Collaborator
IRCCS Fondazione Stella Maris
Collaborator
Istituto Neurologico Mediterraneo Neuromed S. R. L
Collaborator
IRCCS San Raffaele Roma
Collaborator
Fondazione Don Carlo Gnocchi Onlus
Collaborator
Ospedale San Raffaele
Collaborator
IRCCS Centro Neurolesi Bonino Pulejo
Collaborator
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Collaborator
Istituto Auxologico Italiano
Collaborator
Istituti Clinici Scientifici Maugeri SpA
Collaborator
Fondazione IRCCS San Gerardo dei Tintori
Collaborator
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