The present study sought to explore the predictive value of radial wall strain (RWS, derived solely from angiograms) for coronary artery lesion progression compared with lesion vulnerability assessed by optical coherence tomography (OCT). The lesion progression at 1 year was defined as an increase of ≥20% in diameter stenosis based on quantitative coronary angiography (QCA) evaluation.
Age ≥18 years
Acute myocardial infarction ≤ 45 days
Planned coronary angiography examination or potential interventional treatment
The presence of at least 1 non-flow-restricting lesion (visually estimated diameter stenosis: 30%-80%; QFR > 0.80) in any non-infarct related artery with RVD ≥2.5 mm by visual assessment
Cardiogenic shock
Pregnant or woman of child-bearing potential
Life expectancy less than 1 year for non-cardiac causes
Unable to tolerate contrast agents or anticoagulant/antiplatelet therapy
Adult study participants with acute myocardial infarction complicated by multi-vessel coronary artery diseases within 45 days.
Cohort
Prospective
Not listed
Lesion progression assessed by QCA
Defined as an increase of ≥20% in diameter stenosis based on QCA evaluation
Incidence of major adverse cardiac events (MACE)
Defined as a composite endpoint of all-cause death, new myocardial infarction, and unplanned revascularization
Incidence of all-cause death
Including cardiac or non-cardiac death
Incidence of new myocardial infarction
Incidence of unplanned revascularization
Including infarction-related/non-infarction-related vessel revascularization
Click on the lead sponsor to view all of their trials.
