Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAin Shams University

About this trial

This study aims to compare the efficacy (in terms of vein clearance) and safety of Nd:YAG laser combined with injection sclerotherapy versus diode laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18-60 years.

Both sexes.

Presence of reticular veins and/or telangiectasias (CEAP classification C1).

Fitzpatrick skin types II-V.

Disqualifiers

Pregnancy or lactation.

History of deep vein thrombosis.

Coagulation disorders.

Allergy to sclerosant agents.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Nd:YAG laser

    Device

    Patients will receive Nd:YAG laser (1064 nm) + injection sclerotherapy (CLaCS).

  • Diode laser

    Drug

    Patients will receive Diode laser (980 nm) + injection sclerotherapy (CLaCS).

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Group A (Nd:YAG Group):Experimental treatment 1 intervention
Group B: Group B (Diode Group)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Degree of vein clearance

Degree of vein clearance will be assessed by immediate endpoint response during laser application, defined as either instantaneous disappearance of the vein or an immediate change in vein color.

Time frame
6 months postoperatively

Secondary outcomes

1

Degree of pain

Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable").

Time frame
6 months postoperatively
2

Degree of patient satisfaction

Degree of patient satisfaction will be assessed on a 5-point Likert scale patient satisfaction (1, extremely dissatisfied; 2, unsatisfied; 3, neutral; 4, satisfied; 5, extremely satisfied).

Time frame
6 months postoperatively
3

Incidence of complications

Incidence of complications such as hyperpigmentation, burns, and matting will be recorded.

Time frame
6 months postoperatively
4

Number of treatment sessions required

Number of treatment sessions required will be recorded.

Time frame
6 months postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.