About this trial
This study aims to compare the efficacy (in terms of vein clearance) and safety of Nd:YAG laser combined with injection sclerotherapy versus diode laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged 18-60 years.
Both sexes.
Presence of reticular veins and/or telangiectasias (CEAP classification C1).
Fitzpatrick skin types II-V.
Disqualifiers
Pregnancy or lactation.
History of deep vein thrombosis.
Coagulation disorders.
Allergy to sclerosant agents.
Trial design
Parallel
Treatments tested in this trial
Nd:YAG laser
DevicePatients will receive Nd:YAG laser (1064 nm) + injection sclerotherapy (CLaCS).
Diode laser
DrugPatients will receive Diode laser (980 nm) + injection sclerotherapy (CLaCS).
Treatment groups
Trial outcomes
Primary outcomes
Degree of vein clearance
Degree of vein clearance will be assessed by immediate endpoint response during laser application, defined as either instantaneous disappearance of the vein or an immediate change in vein color.
Secondary outcomes
Degree of pain
Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable").
Degree of patient satisfaction
Degree of patient satisfaction will be assessed on a 5-point Likert scale patient satisfaction (1, extremely dissatisfied; 2, unsatisfied; 3, neutral; 4, satisfied; 5, extremely satisfied).
Incidence of complications
Incidence of complications such as hyperpigmentation, burns, and matting will be recorded.
Number of treatment sessions required
Number of treatment sessions required will be recorded.
Sponsors and contacts
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