Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBenha University
About this trial
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones. Participants with renal stones measuring 2-3 cm will be randomly assigned to either tubeless percutaneous nephrolithotomy with nebulized Glubran 2 used to seal the access tract or conventional percutaneous nephrolithotomy with placement of a nephrostomy tube. The study will evaluate whether the Glubran 2-assisted tubeless technique is safe and effective and whether it can reduce postoperative pain, bleeding, hospital stay, urine leakage, and other complications while maintaining a satisfactory stone-free rate.
Eligibility criteria
Qualifiers
Age 18 years or older.
Single or multiple renal stones measuring 2-3 cm.
Renal stones located in an anatomical position suitable for percutaneous nephrolithotomy.
Participant considered suitable for PCNL under general anesthesia.
Disqualifiers
Active urinary tract infection.
Renal stones in an anomalous kidney.
Uncontrolled hypertension.
Uncontrolled diabetes mellitus.
Trial design
Treatments tested in this trial
- Nebulized Glubran 2-Assisted Tubeless PCNL
- Conventional PCNL With Nephrostomy Tube
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov