Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Aberdeen
About this trial
The purpose of the study is to understand the composition of the nerves supplying the facet joints in low back.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Be aged 18 or over
be able to give informed consent
scheduled to undergo lumbar spinal surgery
Disqualifiers
Children under 18 years old
Vulnerable adults
Adults with incapacity
Inability to provide informed consent
Trial population
The study population will be the cohort of patients who are scheduled to undergo lumbar spinal surgery. The potential population will be identified from the patients who are being invited for the surgery. All prospective participants will be sent an invitation letter and Participant Information Sheet along with their the clinical appointment letters.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Spinal surgery
Procedure/SurgeryIn participants who undergo elective lumbar spinal surgery and consented for research, the medial branch and dorsal rami will be harvested for histological analysis.
Histology
Other interventionThe harvested nerves will be fixed, cut into smaller sections. Analysis of macroscopic and light microscopic sections will be carried out
Treatment groups
20 Participants
are divided into 1 treatment groupGroup A: Active group2 interventions
Trial outcomes
Primary outcomes
1
Nerve Histology
Percentage of nerves containing more than 50% sensory fibres in lumbar dorsal rami/medial branches to assess whether they are sensory or motor nerves
Time frame
one yearSponsors and contacts
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Source ClinicalTrials.gov