Neural Changes in Stroke Patients During Challenging Walking Tasks.
ConditionStroke
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorNanjing Medical University
About this trial
For stroke patients, a challenging, unfamiliar, and more difficult task may increase the likelihood of brain activation to stimulate recovery. Pedal walking and walking with eyes-covered are both difficult and challenging tasks for stroke patients. The investigators intend to study the biomechanics and neural mechanisms of challenging pedal walking and walking with eyes covered.
Stroke participants will wear electroencephalogram electrode caps and perform three tasks: walking on a flat surface for 60 seconds, walking on pedal for 60 seconds, and walking with eyes covered for 60 seconds.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
First-time occurrence of stroke confirmed by computed tomography or magnetic resonance imagingClinical diagnosis of stroke
Disease duration of more than 14 days， less than 1 year
Able to walk independently but with a lingering abnormal gait
Disqualifiers
Lesions accumulate in the brainstem
Lesions accumulate in the cerebellum
Impaired vision
Severe cognitive impairment
Trial population
Stroke patients, including outpatients and inpatients.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
pedal walking
Other interventionPedal walking is a challenging walking task that can be used as a form of physical therapy for stroke participants.
visual occlusion
Other interventionWalking with eyes-covered is a challenging walking task that can be used as a form of physical therapy for stroke participants.
Treatment groups
60 Participants
are divided into 1 treatment groupGroup A: stroke participants2 interventions
Trial outcomes
Primary outcomes
1
Weight Phase Lag Index
The Weighted Phase Lag Index (WPLI) is a measure used to quantify phase synchronization in electrophysiological data.Continuously measure the connectivity of the coupling of neural oscillatory activity in the brain, while being statistically more powerful in detecting changes in signal phase synchronization.The WPLI ranges from 0 to 1, with 0 indicating no phase synchronization and 1 indicating complete phase synchronization.
Time frame
The study was an observational cross-sectional study with data collected at the same time as the trial was being conducted, so the duration was 60 seconds2
Relative power
The electroencephalogram signal in the time domain is converted into the relevant information in the frequency domain, the frequency bands are divided, and the relative power results of each channel in each frequency band are derived. Among them, delta:1-4Hz, theta:4-8Hz, alpha:8-15Hz, beta:15-30Hz, gamma:30-45Hz.
Time frame
The study was an observational cross-sectional study with data collected at the same time as the trial was being conducted, so the duration was 60 secondsSponsors and contacts
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Source ClinicalTrials.gov