The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.
patients present within 12 hours after acute carbon monoxide poisoning;
age older than 16 years.
pregnant women；
patients receive oxygen therapy before presentation;
have history of acute carbon monoxide poisoning within 1 year;
have been diagnosed any of the following disease: Parkinson disease; cognitive disorder, psychiatric disorders, sequelae of cerebral infarction or hemorrhage, chronic kidney disease and receive hemodialysis, congestive heart failure ( NYHA class III-IV)
All the patients with acute carbon monoxide poisoning would be recruited from the First Hospital of Jilin University.
Cohort
Prospective
No intervention
Other interventionNo intervention will be given
Changes of Mini-mental State Examination (MMSE) score at 6 weeks
Score ranges from 0 to 30, a lower score means a worse outcome.
Changes of Mini-mental State Examination (MMSE) score at 6 months
Score ranges from 0 to 30, a lower score means a worse outcome.
Changes of Mini-mental State Examination (MMSE) score at 12 months
Score ranges from 0 to 30, a lower score means a worse outcome.
Changes of Montreal cognitive assessment (MoCA）score at 6 weeks
Score ranges from 0 to 30, a lower score means a worse outcome.
Rates of cardiovascular and cerebrovascular events
Cardiovascular and cerebrovascular events includes：cardiac arrest, myocardial infarction, cerebral hemorrhage, and cerebral infarction. A patient develops any of the former diseases during following up would be record as 1 event.
Rates of accidental injury
Accidental injuries may include accidental fall, fracture, traffic accident etc. A patient develops any of the former during following up would be record as 1 event.
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