About this trial
The research study is being conducted to better understand parts of the human brain called the cortex, basal ganglia, thalamus, and cerebellum in patients with movement disorders (such as Parkinson's disease, essential tremor, dystonia, or ataxia). These brain structures are involved in movement disorders. This study attempts to better understand the brain electrical activity associated with these disorders, both in patients with and without deep brain stimulation (DBS). Recordings are made from the scalp with a noninvasive electrode and/or through the DBS stimulator if the participant has a stimulator model that is able to sense brain activity. These recordings are analyzed along with measures of movement disorder symptoms to identify brain signal signatures of symptoms.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients 18 years of age and above
Parkinson's disease
Dystonia
Tremor, including essential tremor
Disqualifiers
None
Trial design
Parallel
Treatments tested in this trial
Prescribed Medications
Other interventionparticipant's movement disorders medications, prescribed by their treating physician
Deep brain stimulation adjustment
Other interventionDeep brain stimulator parameters may be adjusted within normal clinical limits
Treatment groups
Trial outcomes
Primary outcomes
Neural signal biomarkers
Spatiotemporal patterns of brain neural activity (neural signal biomarkers / neurophysiologic signatures) associated with movement disorders symptoms.
Sponsors and contacts
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