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Neurosurgical Outcome Network

ConditionsAneurysmsArteriovenous MalformationsCavernomasSkull Base TumorsMoyamoya DiseaseDural FistulasSubdural HematomaExtradural HematomaSubarachnoid HemorrhageHydrocephalusParkinson&Amp;#39;s DiseaseSpasticityTrigeminal NeuralgiaCraniofacial PainNeuropathic PainTremorDystoniasObsessive-compulsive DisorderDrug-resistant EpilepsyDepressionNormal Pressure HydrocephalusTumors of Peripheral NervesChiari Malformation Type 1
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

About this trial

The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upon by the participating centers. Standardizing the evaluation of outcomes and predictors improves the quality of research, allows for data comparison, and facilitates a "common language" in routine clinical practice. Most importantly, it influences therapeutic decisions in various neurosurgical conditions. Clinically, the identified predictors can also be used during preoperative assessments to provide more precise guidance to patients undergoing surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Neuro-oncological pathology: supratentorial and subtentorial tumors, intra and extra axial tumors excluding the skull base (anterior, middle and posterior fossa; sellar and parasellar region)

Basicranial pathology: tumors originating from the anterior cranial fossa, middle cranial fossa and posterior cranial fossa, sellar region with or without supratentorial/parasellar development.

Vascular pathology: aneurysms, AVMs, cavernomas, other pathologies (Moyamoya disease, dural fistulas, nontraumatic hematomas)

Traumatic pathology: diffuse damage (nonvisible diffuse damage, diffuse damage, diffuse damage with edema, diffuse damage with shift) and focal damage (acute/subacute/chronic subdural hematoma, extradural hematoma, subarachnoid hemorrhage, intraparenchymal hematoma, fractures); hydrocephalus. The inclusion criterion for chronic subdural hematoma is recent bleeding for TBI with CT finding of chronic subdural hematoma candidate for evacuation surgery.

Disqualifiers

For cognitive and psychological assessment: patients with psychiatric diseases in history and/or taking psychotropic drugs; presence of overt cognitive decline (not due to the injury) in history; patients younger than 18 years old.

Trial population

Patients older than 18 years old, with neurosurgical pathology

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Collect data

Collect and describe the pre- and postoperative clinical status in various neurosurgical pathologies.

Time frame
5 years
2

Collection data

Collect and describe the pre- and postoperative cognitive status in various neurosurgical pathologies.

Time frame
5 years
3

Collection data

Collect and describe the pre- and postoperative psychological status in various neurosurgical pathologies.

Time frame
5 years

Secondary outcomes

1

Identify Predictors

Identify outcome predictors.

Time frame
1 year

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Lead sponsor

Source ClinicalTrials.gov
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