New Perspectives in Adenomyosis Pathogenesis With Epigenetic Analysis and miRNAs
ConditionAdenomyosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorUniversité Catholique de Louvain
About this trial
Objectives:
To identify differentially expressed miRNAs in the blood of adenomyosis patients in view to develop new diagnostic methods
Hypotheses Circulating miRNAs may be abnormally expressed in patients suffering from adenomyosis and could be used to diagnose the disease
Study Design Blood samples will be collected from healthy subjects and adenomyosis patients and miRNAs will be isolated and analyzed to detect potential differences.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥ 18 years
Pre-menopausal
Disqualifiers
HIV or Hepatitis-positive
having participated in another clinical study in the 12 months prior to recruitment
presenting symptoms of endometriosis
Trial population
Female patients visiting the service de Gynécologie of the CUSL for the purpose of surgical intervention in the context of uterine adenomyosis
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Circulating-mirna
Diagnostic testA single blood sample (1 tube of 10 ml) on the day of the patient's visit to the service de Gynécologie of the CUSL.
Treatment groups
50 Participants
are divided into 2 treatment groupsGroup A: Control group (N=25)1 intervention
Group B: Adenomyosis group (N=25)1 intervention
Trial outcomes
Primary outcomes
1
Circulating-miRNA as diagnostic biomarkers
Sequencing miRNA
Time frame
Throughout the entire study, aproximately during 6,5 yearsSponsors and contacts
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Source ClinicalTrials.gov