New Therapeutic Approach Against BK Virus Infection Based on Monoclonal Antibodies

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Strasbourg, France

About this trial

BK virus (BKV) infection has a major negative impact on transplant recipients. No BKV-specific antiviral therapy is available, so there is an urgent need to develop new anti-BKV preventive and therapeutic strategies.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

BK positive

adult

ok to participed to research

Disqualifiers

under guardianship

under curatorship

opposed to research

deprived of liberty

Trial population

\- Adult patient with a posititive serology BK confirmed

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Ability of the isolated monoclonal antibodies to neutralize all 3 BKV genotypes

The neutralization titer will be defined as the dilution of the sample that produced 50% inhibition of pseudovirion infectivity (IC50)

Time frame
5 years

Secondary outcomes

Other outcomes

Sponsors and contacts

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