NIRS in Congenital Heart Defects - Correlation With Echocardiography

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-7
SponsorMcGill University Health Centre/Research Institute of the McGill University Health Centre

About this trial

Neonatal patients with congenital heart defects (CHD) have changing physiology in the context of transitional period. Patients with CHD are at risk of low perfusion status or abnormal pulmonary blood flow. Near infrared spectroscopy has been used in neonatal intensive care units (NICU) to measure end-organ perfusion. The investigator plan on monitoring newborns with CHD admitted to the NICU with NIRS and echocardiography during the first week of life and correlate measures of perfusion from Dopplers to cerebral and renal NIRS.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

All newborns with tetralogy of fallot, truncus arteriosus, D-transposition of great arteries, PS, AS, coarctation of the aorta, DILV, AVC, DORV, HLHS, TA and PAIVS consecutively admitted at our institution (Montreal Children's Hospital) neonatal intensive care unit (NICU) from January 2018 to January 2020.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • NIRS evaluation

    Device

    NIRS will be used for measurement of cerebral and renal saturation.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Correlation between cerebral saturation and ACA doppler

Time frame
Measures from Day 0 to Day7
2

Correlation between aortic doppler and renal NIRS measures

Time frame
Measures from Day 0 to Day7

Secondary outcomes

1

Correlation between LV performance by STE and Csat and Rsat by NIRs

Time frame
Measures from Day 0 to Day7

Other outcomes

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