NLR, ELR and SII Index as Biomarkers of Asthma Control

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorShaimaa Ali Mohammed

About this trial

This is Case control study aims to study Neutrophil-to-Lymphocyte Ratio (NLR), Eosinophil-to-Lymphocyte Ratio (ELR), and Systemic Immune Inflammation (SII) Index as Biomarkers of Asthma Controlin adult patients with bronchial asthma.

This study will investigate the association between these inflammatory indices and the level of asthma control to assess their potential value as simple ,readily available and cost -effective biomarkers in clinical practice.

Eligibility criteria

Qualifiers

Adult patients aged > 18 years.

Confirmed diagnosis of bronchial asthma according to Global Initiative for Asthma (GINA) guidelines.

Patients who provided informed consent to participate in the study.

Disqualifiers

Patients with chronic respiratory diseases other than asthma.

Acute respiratory infection within the previous 4 weeks.

Patients with hematological disorders, malignancies, autoimmune diseases, or systemic inflammatory conditions that might affect blood cell counts.

Patients taking systemic steroids, experiencing acute asthma attack (because infection may affect neutrophil level).

Trial design

Treatments tested in this trial

  • Complete blood count

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Shaimaa Ali Mohammed

Lead sponsor

Assiut University

Sponsor institution