The primary aim is to determine whether non-dipping status is associated with adverse repolarization markers and impaired myocardial mechanics compared to dipper hypertensive patients. Secondary analyses will compare these findings among resistant vs. non-resistant and controlled vs. uncontrolled hypertensive groups. This study may provide new insights into the prognostic significance of blood pressure dipping patterns in hypertensive patients.
Adults ≥18 years old
Diagnosed with essential hypertension
Completed 24-hour ambulatory blood pressure monitoring (ABPM)
Availability of good-quality 12-lead ECG
Body mass index (BMI) > 34.9 kg/m²
Atrial fibrillation or atrial flutter
Use of QT-prolonging medications
End-stage renal disease or liver failure
Adult patients (≥18 years) with essential hypertension attending the Cardiology Department at Assiut University Heart Hospital. All participants will undergo 24-hour ambulatory blood pressure monitoring, electrocardiography, and echocardiography to classify them into dipper and non-dipper groups
Other
Prospective
Nocturnal Blood Pressure Dipping
Other interventionPatients will be classified as dippers (≥10% nocturnal BP fall) or non-dippers (\<10% nocturnal BP fall) based on 24-hour ambulatory blood pressure monitoring.
Effect of nocturnal BP dipping on ECG markers of ventricular repolarization
Evaluation of QTc, QT dispersion, and Tp-Te interval in dipper vs. non-dipper hypertensive patients, correlated with echocardiographic changes
Repolarization and echocardiographic changes in resistant vs. non-resistant hypertension
Comparison of ECG and echocardiographic markers between resistant and non-resistant hypertensive groups
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