Nomogram for Predicting Biliary Complication
ConditionLiver Transplant Disorder
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSun Yat-sen University
About this trial
The goal of this observational study is to develop a nomogram model to predict biliary complications within 90 days in adult patients after liver transplantation. The main questions it aims to answer are:
Can the nomogram predict biliary complications within 90 days in adult patients after liver transplantation? What about the performance of the nomogram? Researchers will compare patients' preoperative variables, intraoperative factors, and postoperative outcomes to see what factors are associated with biliary complications.Subsequently, multivariable logistic regression analysis was conducted to evaluate the factors associated with biliary complications occurring within 90 days post-liver transplantation. Finally, a nomogram was developed.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Living donor liver transplantation. ② Split liver transplantation.
Multi-organ transplantation. ④ Missing preoperative baseline indicators and postoperative ultrasound examination results.
Patients undergoing re-transplantation.
Trial population
Retrospective collection of cases of patients who underwent liver transplantation in the Organ Transplantation Department at Sun Yat-sen University First Affiliated Hospital between January 1, 2016, and December 31, 2021.
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
900 Participants
are grouped into 2 trial groupsGroup A: No biliary complication group
Group B: biliary complication group
Trial outcomes
Primary outcomes
1
Body Mass Index (BMI):
Calculated as weight (kg) / height (m²).
Time frame
1-2 days before surgery2
Surgical Technique
Type of technique used (orthotopic, piggyback, or ischemia-free liver transplantation).
Time frame
Intraoperative time3
Weight
Measured in kilograms.
Time frame
1-2 days before surgery4
Height
Measured in meters.
Time frame
1-2 days before surgerySecondary outcomes
1
Transaminase Levels
Measured in units per liter (U/L)
Time frame
24 hours post-surgery.2
ICU Stay Duration
Measured in hours.
Time frame
24 hours post-surgeryLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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