Non-Contrast Versus Contrast-Enhanced MRI in Colorectal Liver Metastases
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University
About this trial
This prospective study aims to compare the diagnostic performance of a non-contrast abbreviated MRI protocol with a contrast-enhanced MRI protocol for the detection and follow-up assessment of colorectal liver metastases.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
- Histologically confirmed colorectal adenocarcinoma
One or more hepatic focal lesions known or suspected to represent colorectal liver metastases
Adequate image quality allowing reliable assessment of hepatic lesions
Patients scheduled to receive chemotherapy allowing assessment of treatment response
Disqualifiers
- Contraindications to gadolinium-based contrast administration
Incomplete MRI examinations
Inadequate image quality preventing reliable assessment
Contraindications to MRI examination
Trial population
Patients with histologically confirmed colorectal adenocarcinoma and suspected hepatic metastases referred to the Diagnostic and Interventional Radiology Department at Assiut University Hospitals.
Trial design
Design model
Case-only
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
40 Participants
are grouped into 1 trial groupGroup A: Single cohort: Patients with Colorectal Liver Metastases
Trial outcomes
Primary outcomes
1
Sensitivity of non-contrast MRI for detection of hepatic metastases
Sensitivity of the non-contrast abbreviated MRI protocol for detection of hepatic metastases, using contrast-enhanced MSCT as the reference standard.
Time frame
BaselineSecondary outcomes
1
Sensitivity of contrast-enhanced MRI for detection of hepatic metastases
Sensitivity of the contrast-enhanced MRI protocol for detection of hepatic metastases, using contrast-enhanced MSCT as the reference standard.
Time frame
Baseline2
Specificity of non-contrast MRI
Specificity of the non-contrast abbreviated MRI protocol for detection of hepatic metastases.
Time frame
Baseline3
Specificity of contrast-enhanced MRI
Specificity of the contrast-enhanced MRI protocol for detection of hepatic metastases.
Time frame
Baseline4
Number of hepatic lesions detected by non-contrast MRI
Mean number of hepatic metastatic lesions detected by the non-contrast MRI protocol.
Time frame
BaselineLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: