Non-Invasive Prediction of Necrotizing Enterocolitis in Preterm Neonates with Feeding Intolerance Using Fecal Lipocalin-2 and Electrical Cardiometry

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-28
SponsorAin Shams University

About this trial

Prospective observational study to evaluate the efficiency of using electrical cardiometry in combination with fecal lipocalin-2 for prediction of NEC in preterm neonates with feeding intolerance

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Chromosomal anomaly or multiple congenital malformations.

Patient with surgical malformation of the intestinal tract (i.e. omphalocele, gastroschisis, malrotation, intestinal atresia)

Patient diagnosed as hypoxic ischemic encephalopathy.

Trial population

Preterm neonates with gestational age ≤ 35 weeks, admitted to NICU, started enteral feeding and diagnosed as having feeding intolerance defined as stage IA and IB by modified bell's staging

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

42 Participants
are grouped into 1 trial group
Group A: feeing intolerance group

Trial outcomes

Primary outcomes

1

Electrical cardiometry for prediction of NEC in preterm neonates with feeding intolerance

low cardiac output measured by electrical cardiometry predict NEC in preterm with feeding intolerance

Time frame
48 hours

Secondary outcomes

1

Fecal lipocalin-2 for prediction of NEC in preterm neonates with feeding intolerance

High level of lipocalin-2 in stool sample predict NEC in preterm neonates with feeding intolerance

Time frame
48 hours
2

SMA flow in prediction of NEC in preterm neonates with feeding intolerance

low flow through SMA predict NEC in preterm neonates with feeding intolerance

Time frame
48 hours

Other outcomes

Sponsors and contacts

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