Nudging Preventive Screening Via Message Framing and Bundling

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-74
SponsorUniversity of Chile

About this trial

This study is a randomized controlled field experiment embedded in the medical institution Early Diagnosis Program in Chile. Participants with two exams pending (a cancer screening test and a chronic disease test for diabetes and dyslipidemia) will be randomly assigned across a 3 × 3 factorial design: three message framing conditions (Basic, Risk/Importance, Peace of Mind) crossed with three exam-type conditions (cancer screening only, chronic disease test only, or both exams). Participants with only a cancer screening pending will be assigned to the 3 framing conditions and be encouraged to get the cancer screening.

In both cases, participants are assigned to each experimental arm at twice the rate of an additional arm receiving the standard message currently used by the medical institution. This standard-message arm is included for operational purposes, is not part of the pre-specified analyses, and is thus not described in the "Arms and Intervention" section (or counted for "number of arms").

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Has at least one pending cancer screening (breast, colorectal, cervical, or prostate) within the contact window, as determined by the medical institution

Aged 21 to 74 years

Has a valid phone number on file

Eligibility is determined operationally before randomization (ex-ante)

Disqualifiers

Participants whose WhatsApp message was not successfully delivered, as reported by the third-party software used by the medical institution.

Trial design

Design model

Factorial

Treatments tested in this trial

  • Basic cancer screening message

    Behavioral

    Patients receive a WhatsApp message naming their recommended cancer screening exam and describing it as the test recommended for their age group.

  • Basic chronic disease test message

    Behavioral

    Patients receive a WhatsApp message naming the recommended chronic disease test and describing it as the test recommended for their age group.

  • Basic combined message

    Behavioral

    Patients receive a WhatsApp message naming both the recommended cancer screening and the chronic disease test, and describing them as the tests recommended for their age group.

  • Risk framing cancer screening message

    Behavioral

    Patients receive a WhatsApp message naming their recommended cancer screening exam and emphasizing that (1) the recommendation is based on health risks common to their age group and (2) early detection can be life-saving

  • Risk framing chronic disease test message

    Behavioral

    Patients receive a WhatsApp message naming the recommended chronic disease test and emphasizing that (1) the recommendation is based on health risks common to their age group and (2) early detection can be life-saving.

  • Risk framing combined message

    Behavioral

    Patients receive a WhatsApp message naming both exams and emphasizing that (1) the recommendation is based on health risks common to their age group and (2) early detection can be life-saving.

  • Peace of mind framing cancer screening message

    Behavioral

    Patients receive a WhatsApp message naming their recommended cancer screening exam and emphasizing that getting the exam done on time will give them peace of mind about their health.

  • Peace of mind framing chronic disease test message

    Behavioral

    Patients receive a WhatsApp message naming the recommended chronic disease and emphasizing that getting the exam done on time will give them peace of mind about their health.

  • Peace of mind framing combined message

    Behavioral

    Patients receive a WhatsApp message naming both exams and emphasizing that getting the exams done on time will give them peace of mind about their health.

Treatment groups

235,000 Participants
are divided into 9 treatment groups

9

Treatment groups

See each treatment group below.

Group A: Basic/Control × CancerActive comparator 1 intervention
Group B: Basic/Control × chronic disease testActive comparator 1 intervention
Group C: Basic/Control × BothActive comparator 1 intervention
Group D: Risk/Importance × CancerExperimental treatment 1 intervention
Group E: Risk/Importance × Chronic Disease TestExperimental treatment 1 intervention
Group F: Risk/Importance × BothExperimental treatment 1 intervention
Group G: Peace of Mind × Cancer screeningExperimental treatment 1 intervention
Group H: Peace of Mind × chronic disease TestExperimental treatment 1 intervention
Group I: Peace of Mind × BothExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Screening Engagement Response

Binary indicator of whether the patient clicks "Yes, I want help" or provides an equivalent affirmative response via WhatsApp within 7 days of receiving the message (1), or does not take either action (0). Used to test H1a, H1b, H1c, and H2a.

Time frame
7 days after message delivery
2

Cancer Screening Appointment

Binary indicator of whether the patient schedules the recommended cancer screening exam within 7 days of receiving the message (1) or does not (0). Used to test H2b

Time frame
7 days after message delivery
3

Chronic Disease Testing Appointment

Binary indicator of whether the patient schedules the recommended chronic disease test within 7 days of receiving the message (1) or does not (0). Used to test H2c.

Time frame
7 days after message delivery

Secondary outcomes

1

Screening Appointment Scheduling

Binary indicator of whether the patient schedules the specific test recommended in the message within 7 days of receiving it (1) or does not (0). Used to test H1a, H1b, and H1c.

Time frame
7 days after message delivery
2

Screening Test Completion

Binary indicator of whether the patient completes the specific test recommended in the message within 12 weeks of receiving it (1) or does not (0). Used to test H1a, H1b, and H1c

Time frame
12 weeks after message delivery
3

Any Test Appointment Scheduling

Binary indicator of whether the patient schedules any of the tests recommended in the message within 7 days of receiving it (1) or does not (0). Used to test H2a.

Time frame
7 days after message delivery
4

Any Test Completion

Binary indicator of whether the patient completes any of the tests recommended in the message within 12 weeks of receiving it (1) or does not (0). Used to test H2a.

Time frame
12 weeks after message delivery

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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