Nutri-CAP: Nutrition for Children, Adolescent Girls, and Pregnant Women in Slums of Dhaka City

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-39
SponsorInternational Centre for Diarrhoeal Disease Research, Bangladesh

About this trial

The objective of the research project is to establish an evidence-based sustainable nutrition service delivery platform for optimizing pregnancy weight gain, increasing dietary diversity of adolescent girls, and ensuring proper physical growth of under 2 children.

Hypothesis

1. Pregnant Women: Intensive nutrition and WASH counseling, iron-folate, calcium supplementation during pregnancy, can improve gestational weight gain and improve hemoglobin status in pregnant women in a slum of Dhaka city 2. Adolescent girl: Iron and zinc supplementation and nutrition counseling on dietary diversity could improve nutritional status and dietary diversity score in adolescent girls of slums in Dhaka 3. Children \<2 years: Counselling on IYCF, growth monitoring, and promotion, ensuring six-monthly vitamin A supplementation, counseling on WASH, treatment of acute malnutrition, and daily 1 egg supplementation for 3 months for severely stunted children can improve the nutritional status of children 4. Counselling to improve Water, Sanitation and Hygiene (WASH) practice: WASH intervention can improve EED biomarkers

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 18-39 years

Before 16 weeks of gestation

BMI 15-24.99 kg/m2 measured on enrolment

Have the plan to stay in the study area till delivery

Disqualifiers

Subject not willing to provide consent

Subject has the plan to migrate outside of the study area during the study period

Subject has a plan to go elsewhere ( village/ parents' house) for delivery

Any reported/diagnosed chronic diseases (such as hypertension, heart disease, chronic obstructive pulmonary disease, chronic kidney disease, chronic liver disease, pancreatic diseases, diabetes mellitus, thyroid dysfunction, immunological diseases, malignancy, or any other diseases which could impede compliance with the study protocol)

Trial design

Design model

Parallel

Treatments tested in this trial

  • Experimental - Intensive nutrition counselling for pregnant, adolescent and under2 children

    Behavioral

    Pregnant women: Intensive dietary counseling using diet chart for locally available food, and to attend antenatal care services from local ANC providers, daily Iron, folic acid, and calcium supplementation. Adolescent girls: Group sessions in the nutrition centers with the adolescent girls will be conducted twice monthly for 6 months. Iron and folic acid (200 mg ferrous fumarate and 400 μg folic acid); once weekly for 3 months; zinc 10 mg daily for 1 month. Children \<2 years: Behavioral counseling sessions through monthly home visits on Infant and Young Child feeding, Growth monitoring and promotion, and water sanitation and hygiene, and food safety. Intensive WASH counselling: Intensive WASH counseling will be provided to separate group of child participants twice a month for 6 months. Severely stunted children: 1 egg supplementation for 3 months and 1 sachet of multiple micronutrient powder (1 RDA of vitamin A and C, iron-folic acid, and zinc) daily for 2 months.

Treatment groups

3,278 Participants
are divided into 2 treatment groups
Group A: ExperimentalExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Gestational weight gain

Change in gestational weight gain and rate of weight gain in the pregnant woman

Time frame
From the 16th week of gestation to child birth
2

Dietary Diversity

Change in Dietary Diversity of Adolescent Girl

Time frame
6 months
3

Improve linear growth

Change in length for age z-score of children less than 2 years

Time frame
1 year
4

Improved maternal WASH practices

Improvement in maternal WASH practics will be assessed through use of safe water, handwashing practice during critical times, use of hygienic/ improved toilet using a structured questionnaire

Time frame
6 months

Secondary outcomes

1

Hemoglobin level of adolescent girl

A change in hemoglobin level Adolescent Girl

Time frame
6 months
2

IYCF indicators

A change in WHO's core IYCF indicators for Children \<2 years

Time frame
1 year

Other outcomes

1

Hemoglobin level of Pregnant woman

A change in hemoglobin level of Pregnant woman

Time frame
16 week of pregnancy to child birth

Sponsors and contacts

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