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Nutritional Responses to Acute Exercise Performed on the LipoxMax in Obese Adolescents

ConditionsWeight GainWeight LossEating AttitudesObese Adolescents
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-16
SponsorCentre Hospitalier Emile Roux

About this trial

Primarily over the past 20 years, it has been shown that physical activity not only leads to energy expenditure but can also indirectly influence energy intake and feelings of hunger in both lean and obese adults, suggesting that physical activity has a dual effect on energy balance.

Studies in children and adolescents are less common, but it now seems clear that their energy intake is affected by physical exercise ) depending on their weight status.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adolescents aged 12 to 16 (inclusive), at Tanner stage 3-5,

With obesity defined as a body mass index (BMI) above the 95th percentile according to international growth charts,

Adolescents enrolled in the social security system or an equivalent program,

Adolescents who have been informed and have provided written consent to participate in the study

Disqualifiers

Refusal to participate in the study,

Refusal of consent by legal guardians,

Regular use of tobacco or alcohol,

Special dietary restrictions,

Trial design

Design model

Single group

Treatments tested in this trial

  • The participants in this study are adolescents with obesity (with a Body Mass Index above the 95th percentile on international growth charts)

    Other intervention

    This study aims to understand how physical exercise performed at a specific intensity that promotes fat utilization (called LipoxMax) influences food intake, hunger, and food preferences in adolescents with obesity. Following an initial screening visit to verify eligibility criteria and assess dietary habits, participants undergo a measurement visit at Clermont-Ferrand University Hospital, which includes anthropometric assessments (height, weight, waist and hip circumferences), body composition measurements (body fat, muscle mass, bone structure), and a bicycle ergometer test to determine their LipoxMax intensity. The adolescents then undergo two experimental visits at the AME2P laboratory in Clermont-Ferrand, conducted in random order and spaced at least five days apart. At each visit, they arrive having fasted, consume a standardized breakfast, and then rest until 11:00 a.m. They then either rest for 40 minutes (control condition) or perform a 40-minute exercise session at LipoxMax.

Treatment groups

18 Participants
are divided into 1 treatment group
Group A: InterventionOther 1 intervention

Trial outcomes

Primary outcomes

1

ad libitum food intake in response to exercise

Method: Meta-Max Indirect Calorimetry The following will be measured here: energy expenditure in kcal/min based on oxygen consumption, as well as fat and carbohydrate utilization based on the respiratory quotient (VCO2/VO2), in mg/min.

Time frame
3 months

Secondary outcomes

1

Feelings of hunger in response to exercise

Method: HUNGER SENSATION QUESTIONNAIRE Patients will have to answer 4 questions with answer situated in between "not at all" and "Very much". The questions are: Are you hungry? Do you feel satiated? How much could you eat again? Would you like to eat something?

Time frame
3 months
2

Hedonic response as measured by food liking and wanting

Their relationship with food will be investigated 15 min before the test meal and then 1 hour after, using the Leeds Foods Preference Questionnaire. The adolescents will be asked to answer a series of questions about their food preferences by selecting their favorite foods from a selection of images during a 10-min computer exercise. During this exercise, they are asked to use a visual analog scale to estimate how much they would like to eat certain foods presented. Based on their choices and the time taken to respond, the LFPQ assesses the adolescents' degree of "liking" and "wanting." The adolescents will be asked to complete this exercise 15 minutes before and after the evening test meal. To avoid influencing food intake at the next meal, the foods presented during the test are not the same as those presented during the meal. As the aim of this exercise is to assess the response of "liking" and "wanting" to food intake, it is necessary to carry it out before and after the meal.

Time frame
3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Centre Hospitalier Emile Roux

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: