Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumption in Patients Who Will be Operate by Thoracotomy and Sternotomy in Cardiac Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorUniversité Libre de Bruxelles

About this trial

The study aims to test the relationship between the preoperative pain threshold and the intraoperative need for opioids.

The objective of the study is to try to predict a patient's analgesic needs based on their objectively determined preoperative pain threshold.

The investigators will include patients scheduled for elective cardiovascular surgery.

The investigators will investigate the correlation between the preoperative pain threshold and intraoperative/postoperative opioid consumption in a highly standardized anesthesia setting.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

ASA 3 patients with scheduled cardiac surgery by thoracotomy or sternotomy

Disqualifiers

Patient refusal,

A body mass index (BMI) > 30 kg/m²,

Allergies to any medication used in typical cardiac anesthesia,

Chronic pain or regular use of analgesics,

Trial design

Design model

Single group

Treatments tested in this trial

  • Measure of the minimal pain threshold with an algometer

    Device

    The measure of the minimal pain threshold is taken the day before the cardiac surgery

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: pain threshold armOther 1 intervention

Trial outcomes

Primary outcomes

1

Correlation between the pressure pain threshold and the consumption of opioid during and after the surgery

After the measure of the minimal pain threshold the day before the surgery, the investigators look at the quantity of Remifentanil which has been given to the patient during the surgery. Then they will look for a correlation

Time frame
From enrollment to the end of opioid administration during hospital stay, up to 6 days after the enrollment

Secondary outcomes

1

Correlation between the pain threshold and the consumption of morphine during the post-operative time

After the measure of the minimal pain threshold the day before the surgery, the investigators look at the quantity of morphine which has been administrated by a PCA (Intravenous Patient-Controlled Analgesia (IV-PCA) with morphine) to the patient during the post-operative time. Then they are looking for a correlation.

Time frame
From enrollment to the end of opioid administration during hospital stay, up to 6 days after the enrollment

Other outcomes

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